A High-gloss, Vegetarian Capsule Ideally Suited for Hygroscopic and Probiotic Fills
Vcaps Plus capsules are ideal for meeting the all important consumer preferences, for natural, vegetarian, plant origin products with little or no additives.
But what really makes Vcaps Plus stand out are its unique attributes:
Exceptional suitability for all types of products, including hygroscopic and moisture-sensitive fills, provides improved stability for sensitive formulations
Gelatin-like filling performance validated on all major filling equipment - provides high manufacturing yields and efficiencies
Resistant to cross-linking and therefore suitable for formulations with gelatin cross-linking potential
Excellent disintegration and dissolution performance
Elegant, crystal-clear, high-gloss appearance - available in an array of color options to enhance and invigorate your brand
Vcaps Plus capsules are starch-free, gluten-free and contain no additives or preservatives claims. The result is an all natural dosage form that complements any product line.
Capsugel Delivers More than Just Capsules
At Capsugel, we understand the requirements and challenges facing the dietary supplement industry. We offer the advantage of meticulous raw materials sourcing, state-of-the-art facilities and equipment, industry leading on-site technical service support as well as knowledgeable support for ISO and GMP operations.
Our global sourcing capabilities facilitate your scale-up needs while our rigorous quality assurance program ensures consistent batch-to-batch performance. Capsugel products are manufactured to cGMP standards, and a Certificate of Analysis is provided with every product batch. And as a global company, our worldwide support staff is ready to help you understand and adhere to regulations in your local market.
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Well Suited for Moisture-Sensitive Formulations
The low moisture content of Vcaps Plus HPMC capsules makes them ideal for challenging applications including:
Formulations that contain hygroscopic materials
Ingredients that are moisture sensitive
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Excellent Machinability & Mechanical Stability
An exclusive capsule design coupled with an elastic polymer structure enables high machine efficiencies.
Extensive field testing on a wide array of capsule filling and blister packaging equipment confirms robust commercial performance.
Vcaps Plus HPMC capsule shells are not affected by moisture. Even in low humidity environments, they maintain their elasticity and ability to resist mechanical breakage.
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Resistant to Cross-Linking
With a well-characterized and stable polymer structure, Vcaps Plus HPMC capsules offer reduced potential for cross-linking. In addition, unlike gelatin, Vcaps Plus will not cross-link with aldehydes.
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Reduced Interference with Formulation Components
With no gelling agents (e.g., carrageenan, gellan gum) or ionic gel promoters, Vcaps Plus capsules help avoid interactions with components of the formulation, interference with buffers used for in vitro dissolution studies, and interactions with dietary components of fed in vivo studies.
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Gelatin-Like Appearance and Greater Consumer Compliance
With an elegant high gloss surface, Vcaps Plus HPMC
capsules appear identical to gelatin, and use a similar
array of colorants including globally-approved iron
oxide pigments.
With no animal-derived components, a wider array
of global dietary needs and preferences are met.
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Consumer Appeal
Hypromellose (HPMC) is a well-characterized and stable material that has been successfully used for years in capsules. It also offers considerable consumer appeal:
Hypromellose (hydroxypropyl methylcellulose) used in Vcaps Plus HPMC capsules complies with USP/NF,
EP and JP standards, and is permitted as a food additive for human consumption in accordance with 21 CFR
172.874 and Regulation (EC) No 1333/2008.
HPMC is included in the US FDA Inactive Ingredients Database, and is generally recognized as a non-toxic
and non-irritant material.
Capsule dietary certifications include Kosher, Halal and Vegetarian Society approved.
Manufactured in accordance with IPEC GMP guidelines, in facilities which are ISO 9001 certified.
Capsugel manufacturing locations have registered Type IV (excipient) Drug Master Files with the US FDA
and Health Canada.
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