Polymer science and engineering have opened a new era of functional development, which offers the potential for selecting the right capsule for different APIs. Capsugel® Vcaps® Plus capsules represent a unique and valuable contribution—they dissolve quickly and predictably at different pH levels and are independent of cations or other food components. Under these conditions, they perform like gelatin. They also offer additional advantages, particularly a lower moisture content, which makes them suitable for hygroscopic and moisture-sensitive drugs and manufacturing processes. Because of the low moisture sensitivity, you have a range of storage options with less chance for brittleness or breakage.
HPMC capsules are inert and robust against cross-linking or the effects of extreme storage conditions. They show excellent mechanical properties for manufacturing and come from a renewable, plant-based resource that’s accepted by the global regulatory community. Capsugel® Vcaps® Plus capsules have the appearance and performance of gelatin while providing important new options to scientists around the world.
 BAS 117 – Capsugel Library – 1000 Patients Give Their Opinion on the Capsule
 Performance qualification of a New Hypromellose Capsule, Part 1. Comparative Evaluation of Physical, Mechanical and Processability Quality Attributes of Vcaps® Plus, Quali-V and Gelatin Capsules. M. Sherry Ku, et a. International Journal of Pharmaceutics, 6 Nov 2009 (epub: 6 Nov 2009), ISSN: 183-3476