Pharmaceutical salts have traditionally been used to address formulation issues, including low solubility. Preliminary in vitro and in vivo studies indicate that lipophilic salt forms can be enabling for lipid formulations by supporting substantially higher drug loadings—more than 10-fold in some cases—and better solubilization than would be possible using free drug alone. Through the use of lipophilic salt forms, formulators can capitalize on the well-established benefits of lipid formulations (e.g., by overcoming product design constraints like the number and/or size of dosage units required). This webinar describes an approach used to prepare lipophilic salt forms for a range of APIs and formulate these salts in concentrated lipid formulations ready for oral delivery.