Formulation And In Vitro Analysis Of A Spray-Dried Albuterol Sulfate And Ipratropium Bromide Combination Inhalation Powder

The goal of this work was to determine the feasibility of formulating and testing a spray-dried combination powder using pharmaceutical compounds typically used to treat asthma and chronic obstructive pulmonary disease (COPD).  Specifically, we describe the manufacturing approach and  in vitro test for a spray-dried ipratropium bromide/ albuterol sulfate dry-powder combination formulation that contained dextran as an excipient. 

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