The Lipid Expert System

Capsugel Dosage Form Solutions’ product development process utilizes a proprietary Lipid Expert System to simplify the development and optimization of lipid-based formulations and significantly increase speed-to-clinic. The expert system can assess a drug candidate’s solubility in a selection of individual excipients in a matter of days. The approach is based on a decision tree linked to a database of experimentally generated phase diagrams and taps into Capsugel’s deep experience in lipid-based formulation. The system offers a QbD formulation approach for self (micro)-emulsifying drug delivery systems or S(M)EDDS.