Multidisciplinary Approach to Optimize and Redefine Bioreactor Operations

This webinar introduces an emerging process-development methodology that is based on applying novel and existing bioreactor monitoring technologies to existing bioreactor processes, coupled with applied mathematics and data-integration techniques across disciplines. This methodology offers an improved way to turn large raw data sets into useful guidance for process development and guidance. The approach uses dielectric spectroscopy, other enhanced process-analytical technologies (PATs), and cell-based bioreactor models with a simple, compact device that automatically obtains samples aseptically at specified intervals for off-line analysis. Case studies are presented.