Liquid-filled Hard Capsule Filling and Sealing Equipment

Capsule Filling and Sealing Equipment

Our specialized liquid filling and sealing equipment enables our liquid filled and semi-solid fill technology to help customers realize the potential of lipid-based formulations for poorly soluble compounds. 

Lonza’s focus on science & engineering has led to the development of proprietary equipment and processing techniques, to provide optimal efficiency, reliability and productivity for our liquid-filled hard capsule clients.

CFS 1200®

  • Lab-scale automated capsule liquid filling and sealing machine combined in one piece of equipment with a nominal throughput of 1,200 filled and sealed capsules per hour. 
  • Enables tamper-proof, semi-solid or liquid-filled capsule dosage forms. 
  • An improved design of the filling and sealing process ensures better control and cleanability. 

CFS-1200 capsule filling and sealing machine



CFS 1500®

  • Achieve nominal throughput of 1,500 filled and sealed capsules per hour with a reproducible and accurate over time capsule sealing process. 
  • The highly capable dosage pump provides increased simplicity, robustness and precision. 
  • Achieve confidence in every accepted capsule - every capsule is weighed and each capsule weight is recorded.

CFS-1500 capsule filling and sealing machine



Licaps® liquid-filled hard capsules

Take advantage of the Licaps® liquid-filled hard capsules (LFHC) to help formulate new compounds with improved functionality while providing an elegant and differentiated product presentation. LFHC and lipid-based technology is routinely used for several functional improvements including bioavailability enhancement, taste and odor masking and combination products.

High protection for outstanding product integrity

  • Fast Release
  • Faster product release facilitates more rapid therapeutic effect

Two-piece body and cap hermetically sealed to form a leak-proof, perfectly airtight, one-piece capsule

Rapid and complete capsule shell disintegration

The one-piece capsule cannot be opened without visible damage

Efficient and highly effective means for delivering liquid drug formulations

High protection of moisture or oxygen-sensitive actives

Can speed substance absorption

Expand Your Products Potential with Licaps® Fusion Technology

  • Straightforward and efficient encapsulation of complex formulations for difficult- to-formulate actives such as low–melting point compounds and high viscosity fills
  • A robust and precise proprietary manufacturing process uses an advanced fusion sealing technology for product integrity that provides high protection for molecules sensitive to oxygen and moisture without the use of banding
  • Licaps® thin shell without plasticizers or preservatives optimizes capsule disintegration making it ideal for products requiring fast release
  • Single or multi-phase dosage form options enable a variety of release profiles allow for novel combinations to address pharmacokinetic challenges and innovative and versatile product offerings which can lead to increased patient compliance