Designing oral drugs for specialized populations, especially pediatrics and the elderly requires innovative approaches to ensure effective treatment. Both swallowability and palatability (especially taste) can heavily impact patient compliance.
Multiparticulate (MP) formulations have proven to be effective approaches in addressing these issues for infants through the institutionalized elderly, while meeting target product profiles and guarding against dose dumping concerns. Specialized capsules can augment the high degree of administration flexibility provided by MP formulations for dosing directly in the mouth, mixing with food, or easy swallowing.
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