Current estimates indicate that more than 70% of new chemical entities require solubilization technology to achieve efficacious plasma exposure. Amorphous solid dispersion technology is a leading approach to improve solubility and dissolution rate of these insoluble compounds by providing a supersaturated concentration of drug in the gastrointestinal environment which often translates to rapid absorption and improved bioavailability.

Bend Research, a division of Capsugel Dosage Form Solutions, will present a webinar that will emphasize the fundamentals of formulating and processing of spray-dried dispersions, including stability assessment, in-vitro performance, and downstream manufacturability.

In this webinar we will show:

Key parameters that indicate amorphous dispersions and specifically spray dry dispersions as an optimal enabling approach.
How the spray drying process can be scaled from tens of milligrams to metric tons.
Best practices for formulation screening and evaluation of stability, performance, and manufacturability of spray-dried dispersions.
Methodologies and tools for spray drying process development and scale-up through clinical supply and commercial manufacturing.

Speakers for this webinar are:

Amber Broadbent, Ph.D., Director Engineering at Bend Research, a division of Capsugel Dosage Form Solutions
Nathan Bennette, Senior Research Chemist at Bend Research, a division of Capsugel Dosage Form Solutions

See the webinar here:

Fundamentals of Spray-Dried Dispersion Technology