Fundamentals of Spray-Dried Dispersion Technology

April 07, 2016

Current estimates indicate that more than 70% of new chemical entities require solubilization technology to achieve efficacious plasma exposure. Amorphous solid dispersion technology is a leading approach to improve solubility and dissolution rate of these insoluble compounds by providing a supersaturated concentration of drug in the gastrointestinal environment, which often translates to rapid absorption and improved bioavailability. Amorphous solid dispersions are typically prepared by using hot-melt extrusion or spray drying processes.

This webinar will focus on the fundamentals of formulating and processing of spray-dried dispersions, including stability assessment, in-vitro performance, and downstream manufacturability.

Moderated by:

  • David Vodak, Ph.D., Bend Research/Capsugel

Presented by:

  • Amber Broadbent, Ph.D., Bend Research/Capsugel
  • Aaron Stewart, M.S., Bend Research/Capsugel
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