Spray-Dried Process and Formulation Considerations for Inhalable Dry Powders

November 02, 2016

Interest in pulmonary delivery of drugs is increasing for both acute and systemic disease conditions. Particle engineering via spray drying is an enabling technology for a number of new API’s destined for lung delivery. Process and formulation attributes are tunable for either small or large molecules, range of API physical properties, and / or desired delivery platform. Robust spray drying approaches have been developed to ensure phase-appropriate formulation development with streamlined timelines and costs. Encapsulation of spray-dried formulations can further enhance speed-to-clinic through commercialization.

During this webinar, we will discuss how target product properties and profiles can be met by altering process conditions and excipient selection for inhalable dry powders.
We will further discuss: 

  • Key considerations for formulating with crystalline or amorphous materials
  • Methods to tailor spray drying conditions to ensure physical and chemical stability of the API
  • Approaches to increase throughput and efficiency
  • Selection criteria for the appropriate formulation excipients to ensure physical stability and aerosolization
  • Necessary analytical testing required

Presented by:

  • Michael Burke, Senior Research Chemist & Inhalation Group Lead

Moderated by:

  • Frédérique Bordes-Picard, Pharmaceutical Marketing Manager
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