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Authentically UC-II®
Experience the Difference of True Undenatured Type II Collagen
UC-II® collagen is the market’s most clinically researched type II collagen, backed by more than 20 studies, including 11 human clinical trials.
The remarkable formula of UC-II® collagen is derived from responsibly sourced uncooked chicken sternum cartilage, a rich and natural source of type II collagen.
Defined by a unique triple helix structure for genuine joint support, UC-II® collagen empowers joint health brands to drive health claims that resonate with consumers.
Welcome to the world of UC-II® - the pinnacle of joint health solutions.
Unlike any other collagen product on the market, UC-II® stands out as the true undernatured type II collagen, offering unparalledled benefits through its unique structure and scientifically validated efficacy.
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About UC-II® collagen
The legacy of UC-II® began over two decades ago. It was originally developed by Dr. Eugene Moore, a devoted father, and science-minded chemical engineer, who was on a mission to find relief for his daughter’s joint discomfort. Lonza is proud to continue Dr. Moore's legacy, supporting thousands of consumers with their joint health and mobility over the years.
Why UC-II® collagen
Achievements
Credible Choice
- Backed by 20+ years of research
- Committed to responsible sourcing
Certifications and Standards
- Self-affirmed GRAS (Generally Recognized As Safe) in the U.S
- NDI (New Dietary Ingredient) FDA notification
- GMP (Good Manufacturing Practice)-certified facility
Quality Assurance
- Each batch tested for purity by GMP-trained employees
- Third party certified labtoratories also conduct tests
- Gluten-free
- Non-GMO
Awards and Recognition
- Recipient of Frost and Sullivan’s 2023 North American Product Leadership Award for the best-in-class undenatured type II collagen in the joint health industry
- No.1 undenatured type II collagen brand globally in terms of market penetration9
Are you ready to deliver your consumers an authentic solution?
Download our FREE brochure "UC-II® undenatured Type-II Collagen" to learn more about why UC-II® is the credible choice for your brand.
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1 Frost and Sullivan, 2023.
2 Lugo JP, Saiyed ZM, Lane NE. (2016). Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study. Nutr J, 15(14). https://doi.org/10.1186/s12937-016-0130-8
3 Lugo et al. (2013). Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers. J Int Soc Sports Nutr, 10(1), 48. https://doi.org/10.1186/1550-2783-10-48
4 Schön et al (2022). UC-II Undenatured Type II Collagen for Knee Joint Flexibility: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study. Journal of integrative and complementary medicine, 28(6), 540–548. https://doi. org/10.1089/jicm.2021.0365.
5 Knaub et al. (2022). UC-II® undenatured type II collagen reduces knee joint discomfort and improves mobility in healthy subjects: a randomized, double-blind, placebo-controlled clinical study. J Clin Trials. 12(1):1000492.
6 Bagi CM, Berryman ER, Teo S, Lane NE. (2017). Oral administration of undenatured native chicken type II collagen (UC-II) diminished deterioration of articular cartilage in a rat model of osteoarthritis (OA). Osteoarthritis Cartilage, 25(12), 2080-2090. https://doi.org/10.1016/j.joca.2017.08.013
7 Yaremenko et al. (2021). Efficacy, tolerance and influence on cartilage metabolism of undenatured collagen type II UC-II (Mercana) in knee OA. PAIN, JOINTS, SPINE, 11(3), 5-12. doi: 616.718.56-001.056.
8 Sahin et al. (2023). The effect of oral administration of undenatured type II collagen on monosodium iodoacetate-induced osteoarthritis in young and old rats. Scientific reports, 13(1), 6499. https://doi.org/10.1038/s41598-023-33763-2
9 Pates, et al. (2023) UC-II(R) undenatured type II collagen data show retention during functional food and beverage protot cessing. Data in Brief, 48, 109216.
10 Natural Marketing Institute. (2020). Supplements/OTC/Rx Trends US and Global Databases — U.S. and European data averages.