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Modern capsule technologies have evolved beyond passive carriers into active components of sophisticated drug delivery strategies. Capsugel® Enprotect® capsules exemplify this shift, offering a next-generation enteric delivery solution designed to protect acid-sensitive APIs and enable targeted release in the small intestine. This review article in the European Journal of Pharmaceutical Sciences examines the changing landscape of capsule design, highlighting Capsugel® Enprotect® capsule’s bi-layered, coating-free approach. Drawing on recent clinical and preclinical data, the publication highlights how Capsugel® Enprotect® capsules support reliable, site specific oral drug delivery for peptides, proteins, and microbiome-based therapies. These advances position Capsugel® Enprotect® capsule as a robust alternative to traditional enteric coating approaches.
Reference:
1. Millet E, O’Shea JP, Griffin BT, Dumont C, Jannin V. Next generation capsules: emerging technologies in capsule fabrication and targeted oral drug delivery. European Journal of Pharmaceutical Sciences. 2025; 214:107277. doi:10.1016/j.ejps.2025.107277. https://www.sciencedirect.com/science/article/pii/S0928098725002751
For full scientific details and data, download the complete article.
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