Comparative Human In Vivo Study of an Immediate Release Tablet Overencapsulated by Gelatin and Hydroxypropyl Methylcellulose Capsules - Impact Of Dissolution Rate on Bioequivalence

Rapid and consistent in-vivo drug dissolution is critical for drug absorption. In-vitro dissolution tests are used to predict in-vivo disintegration and dissolution properties of drug products. The in-vitro disintegration and dissolution times of tablets and capsules can vary significantly based on their composition and processing.