Lonza Engine™ - Biopharmaceutical Capsule Equipment

Capsugel® produces 200 billion hard capsules and approximately 3 billion finished dosage units a year for more than 4,000 customers in over 100 countries. Our vast production capacity allows us to respond quickly and effectively to changing marketplace demands. To help meet the needs of our biopharmaceutical customers, we offer a comprehensive range of equipment.

STATE-OF-THE-ART EQUIPMENT BIOPHARMACEUTICAL CAPSULE EQUIPMENT

Lonza Engine™ offers state-of-the-art equipment designed to address the needs of customers throughout the entire drug development process including:

•Liquid filled hard capsules filling and sealing equipment: support for lipid-based formulations to improve the bioavailability of poorly soluble compounds

•Micronization equipment: flexible solution for micronization process, including different technologies and containment solutions for particles engineering

•Powder Micro-dosing system: precise filling of capsules without excipients or bulking agents

STATE-OF-THE-ART EQUIPMENT

Proven track record
Easy to operate
Flexible systems
Proprietary technology

PEACE OF MIND

Contract services available
Can outsource the extra-capacity to us in a very fast and easy way

SPEED DRUG DEVELOPMENT

Allow to overcome bioavailability challenges
Full range of equipment enabling to speed up the drug development

OUTSTANDING TECHNICAL SERVICE

Global customer service and technical support
Maintenance contract available

POWDER-IN-CAPSULE (MICRODOSING) EQUIPMENT

Lonza offers PIC services using Xcelodose Systems in North America (Xcelience – Tampa, FL) and Europe (Ploermel, FR). Both sites have integrated product development and manufacturing capabilities.

Capsugel® Zephyr™

Dry-powder inhalation (DPI) technology offers a favorable drug development opportunity for respiratory or systemic drug delivery. Delivering a uniform dose in a portable, easy-to-use system, capsule-based DPI devices are a simple and cost-effective way to deliver inhalable medication.

Liquid-Filled Hard Capsules

Capsugel's two-piece liquid-filled hard capsules provide an advanced dosage form specifically designed for secure containment of liquids and semisolids.

Stability, flowability, dissolution rate and bioavailability (BA) are all critical performance parameters impacted by the size distribution of particles. Capsugel® has extensive expertise in particle-size reduction technologies for solid oral and other dosage applications.

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Jet-Milling Micronization

By designing and manufacturing jet mills in house, Capsugel is able to offer a wide variety of jet milling solutions to reduce the particle size of your drug product substance.

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