Next-Generation Capsules: Emerging Technologies in Capsule Fabrication and Targeted Oral Drug Delivery

Capsule technologies have been advancing steadily for decades. Progress in closure mechanisms and manufacturing processes has improved the safety, stability, and reproducibility of capsule-based products. Technologies such as enteric coating now offer the opportunity to enhance bioavailability and stability of sensitive molecules such as peptides, proteins, and RNA-based therapies. Building on the foundation of enteric coating, new innovations such as ready-to-use Capsugel® Enprotect® capsules and 3D printing technologies are expanding the functional possibilities of capsule design. Modern capsule options have evolved beyond passive carriers into active components of sophisticated drug delivery strategies. By examining the changing landscape, this review highlights the growing role of capsules as a next-generation platform for oral targeted drug delivery, capable of meeting increasingly complex therapeutic demands. 

Read the full review to explore how next-generation capsule technologies are shaping the future of oral drug delivery.

Reference:
1.        Millet E, O’Shea JP, Griffin BT, Dumont C, Jannin V. Next generation capsules: emerging technologies in capsule fabrication and targeted oral drug delivery. European Journal of Pharmaceutical Sciences. 2025; 214:107277. doi:10.1016/j.ejps.2025.107277. https://www.sciencedirect.com/science/article/pii/S0928098725002751

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